全新以心理剖析破案的犯罪電視連續劇，故事情節均經過精心佈局，最後揭曉的兇手往往出人意表，甚具追看性。主角本是著名靈媒，被人揭發為騙子後，轉職變成警方的顧問，他以靈敏的感應力以及敏銳的觀察力，協助警方偵破棘手案件，縱使他破案連連，但因他每每不依常規查案，例如違法催眠證人，又熟練地瞞上欺下，所以令其上司大為不滿，二人互相對立。

主角由Simon Baker飾演，他曾演出《穿Prada的惡魔》，並以電視劇《The Guardian》的卓越演出獲金球獎最佳男主角提名。他在劇中幽默風趣的靚仔版神探形象，贏得大批女性觀眾的支持。劇中飾演他的歡喜冤家正是廣為香港觀眾認識、於《逃》第一季飾演女律師Veronica的Robin Tunney。一個硬朗火爆，一個氣定神閒，這對拍檔演來擦出不少精彩火花。

Patrick Jane (series star SIMON BAKER), an independent consultant with the California Bureau of Investigation (CBI), has a remarkable track record for solving serious crimes by using his razor sharp skills of observation. Within the Bureau, Jane is notorious for his blatant lack of protocol and his semi-celebrity past as a former psychic medium, whose paranormal abilities he now admits he feigned. Jane's role in cracking a series of tough high-profile cases is greatly valued by his fellow agents. However, no-nonsense Senior Agent Teresa Lisbon (series star ROBIN TUNNEY) openly resists having Jane in her unit and alternates between reluctantly acknowledging Jane's usefulness and blasting him for his theatrics, narcissism and dangerous lack of boundaries. Lisbon's team includes agents Kimball Cho (series star TIM KANG), Wayne Rigsby (series star OWAIN YEOMAN) and rookie member Grace Van Pelt (series star AMANDA RIGHETTI), who all think Jane's a loose cannon, but admire his charm and knack for clearing cases.